Marie-Claire Janailhac-Fritsch founded Institut De Recherche Et D'Innovation Scientifique SARL and Laboratoire Nature Et Technique SARL. Presently, she occupies the position of Chairman for Guerbet SA and Chairman at Hellébore SAS.

She is also Member of Institut Français Des Administrateurs.

She previously was Chairman at Théâtre du Châtelet and Manager for Fj Immo SARL.

She received an undergraduate degree from École des Hautes Études Commerciales de Paris.